Chronic Migraine Warrior

Chronic Migraine Warrior

Friday, September 28, 2018

Two More CGRP-Drugs Approved by FDA

May 17, 2018 was a Momentous Day for Migraine: First CGRP-Drug Approved by FDA. It was the first FDA approval in a new class of preventive medications developed specifically for migraine.

The month of September has seen the FDA approve two more CGRP-related medications.

On September 14, Teva announced the FDA approval of Ajovy (fremanezumab-vfrm), "a humanized monoclonal antibody that binds to calcitonin gene-related peptide (CGRP) ligand and blocks its binding to the receptor" ( It's available in monthly or quarterly doses, via self-administered, subcutaneous injection(s) from pre-filled syringe(s). The list price is $575 per monthly dose and $1,725 per quarterly dose.

On September 27, Eli Lilly and Company announced the FDA approval of Emgality (galcanezumab-gnlm). It will be available as a once monthly, self-administered, subcutaneous injection. The first month will be two injections, followed by a single monthly injection.(

The CGRP class of medications work to stop CGRP protein from binding to the receptor. Aimovig, is a monoclonal antibody against the CGRP receptor. Both Ajovy and Emgality are monoclonal antibodies against the CGRP protein. There is one more medication that targets the protein that has not yet been approved by the FDA.

Further reading:

Each of the companies that have come to market with CGRP medications for migraine prevention are offering patient support programs, specifically for those with commercial insurance.

Here are the links for the different medications that have been FDA approved:

Thursday, May 17, 2018

Momentous Day for Migraine: First CGRP-Drug Approved by FDA

Huge news! Today, the first-ever preventive developed specifically for migraine was approved by the FDA.
"The drug, Aimovig [erenumab-aooe], made by Amgen and Novartis, is a monthly injection with a device similar to an insulin pen. The list price will be $6,900 a year, and Amgen said the drug will be available to patients within a week." (
This new class of medications targets the calcitonin gene-related peptide (CGRP), which is believed to play a critical role in migraine. There are three other drugs in this class that are aimed at FDA approval in the coming months. During clinical trials, all of these meds have done remarkably well: more effective than the meds currently used for migraine prevention, and with fewer side effects. This could be life-changing!

Further reading:

Wednesday, June 1, 2016

Migraine & Headache Awareness Month 2016

Today is the first day of Migraine and Headache Awareness Month (MHAM) 2016.

The theme for 2016 is Rule Your Headache Disorder: Be actively engaged in your treatment.

Let's spread awareness, diminish stigma, and foster hope and understanding!

This post was written as part of the Migraine and Headache Awareness Month (MHAM) Social Media Challenge.

Thursday, May 5, 2016

Grateful for Being Able to Drive Today

It's been a rocky week. Up one day, down hard the next, repeat. I hope that doesn't happen and wreck my day tomorrow, but I'll take things moment by moment.

For now, I'm grateful for my husband being home from his work trip, and for the things that I was able to do / accomplish. 

I drove more today than I have in almost a year! I went shopping a little today, on my own. It's amazing how independent I felt to be able to drive, take care of things at the pharmacy, and browse / shop... all on my own! I looked back at a previous post I wrote about a similar experience several years ago, Update: Driving Myself (3/25/13).

I was on the phone a lot today, which I don't particularly like... especially when a lot of it was dealing with insurance companies that can't quite interpret the verbiage of my coverage with them. But, I was able to talk with a friend today, which was wonderful! I hope to be able to talk to another dear friend tomorrow. 

My heart is full of gratitude for the little things that can sometimes feel so big!

Monday, May 2, 2016

I Didn't See This One Coming

Weather changes. Increased pain levels.

A storm front came through last night.
Normally, I keep an eye on the weather and do whatever I can to reduce my controllable migraine triggers, so that a weather change won't take me out.

I didn't see last night's coming.

I had trouble getting to sleep last night. But, that's nothing new.
I had an increase in pain last night. Again, nothing new.
I had a few prodrome symptoms, but they seemed minor and I didn't heed their warning.
About an hour or so after I finally fell asleep, I woke to booming thunder and pain.

Even though the temperature drop and storms have long since passed, the throbbing pain, fatigue, aching, nausea, brain fog, vertigo... they all remain.

I didn't see this one coming.

Monday, April 25, 2016

Migraine World Summit - Order

Get your own copy of the 2016 Migraine World Summit today!
The Migraine World Summit has ended, but it's not too late to have access to information from over 30 world leading migraine experts, doctors, and specialists. If you're interested in finding out more, you can go to The Migraine World Summit

Disclaimer: Nothing on this blog is intended as medical or legal advice.

What I write on this site is my own, and if it is someone else's, I take special care to attribute it to the original author. So, please don't use any of my material without proper attribution or permission. Thanks.